Endocrine disruptive compounds and male reproduction

Epigenetic transgenerational effects of endocrine disruptors on male reproduction.

Endocrine-disrupting chemicals generally function as steroid receptor signaling antagonists or agonists that influence development to promote adult-onset disease. Exposure to the endocrine disruptors during the initiation of male reproductive tract development interferes with the normal hormonal signaling and formation of male reproductive organs. In particular, exposure to the endocrine disrup...

Endocrine Monitoring of Reproduction and Stress

Most wild mammals kept in captivity are managed intensively. Under such conditions, the ability to monitor reproductive status can greatly facilitate attempts to enhance breeding success for many species. More specifi cally, objective and reliable methods for monitoring key reproductive events, such as ovulation and pregnancy, not only fi nd widespread application in the management of natural b...

Longer-term and short-term variability in pollution of fluvial sediments by dioxin-like and endocrine disruptive compounds.

Changes in pollutant loads in relatively dynamic river sediments, which contain very complex mixtures of compounds, can play a crucial role in the fate and effects of pollutants in fluvial ecosystems. The contamination of sediments by bioactive substances can be sensitively assessed by in vitro bioassays. This is the first study that characterizes detailed short- and long-term changes in concen...

Testicular Estrogens and Male Reproduction.

Besides somatic cells, aromatase gene expression and its transduction in an active protein in germ cells provides evidence of an additional site for estrogen production within testes of some mammals. Together with the widespread distribution of estrogen receptors in testicular cells, these data illuminate the hormonal regulation of male reproductive function

Physiology of male reproduction.